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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids to determine haptoglobin (HAP), a plasma glycoprotein that irreversibly binds to free hemoglobin. The hemoglobin/haptoglobin complex is removed by the parenchymal cells of the liver, preventing loss of hemoglobin and conserving iron. Haptoglobin is one of the acute-phase reactants. Increased levels of HAP in plasma occur in extensive tissue damage and necrosis; low levels are associated with hemolytic anemia, transfusion reactions, and malaria.
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