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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine thyrotropin (also known as thyroid stimulating hormone) receptor antibodies (TRAb) that bind to thyroid cell membranes at or near the thyrotropin receptor site. TRAbs are found in almost all adult patients with a progressive autoimmune disease of the thyroid gland with lymphocytic infiltration (Hashimoto\'s thyroiditis), in more than 80% of patients with Grave\'s disease, and in patients with idiopathic myxedema (associated with primary hypothyroidism).
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