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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids (typically plasma) to determine the protein alpha-2 macroglobulin (A2MG), a high-molecular-weight protein whose major function is maintaining oncotic pressure during protein loss and that inhibits protease in a different way than other inhibitors. A2MG inhibits a wide variety of enzymes, including trypsin, plasmin, thrombin, and elastase. Increased levels of A2MG in blood (hyperglobulinemia) are seen in nephrotic syndrome.
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