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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids (e.g., serum) to determine the presence of protein alpha-1 Antitrypsin (AAT), also known as protease inhibitor. AAT is a plasma protein that acts as the major inhibitor of trypsin and other proteolytic enzymes. Its concentration rises significantly during acute inflammatory processes (i.e., it is an acute-phase reactant), including surgery, myocardial infarction, infections, and/or in the presence of tumors. Increased levels of AAT typically occur within 24 hours of the injury and decrease in 4 or 5 days. Reduced levels or the absence of AAT is associated with increased risk of emphysema, especially in children.
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