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?:definition
  • A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3\'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3\'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
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