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Human SLX4 wild-type allele is located in the vicinity of 16p13.3 and is approximately 30 kb in length. This allele, which encodes structure-specific endonuclease subunit SLX4 protein, plays a role in both the regulation of endonuclease activity and the recognition of damaged DNA. Mutation of the gene is associated with Fanconi anemia complementation group P.
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