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  • Human NECTIN1 wild-type allele is located in the vicinity of 11q23.3 and is approximately 106 kb in length. This allele, which encodes nectin-1 protein, is involved in both viral entry and the promotion of cell-cell adhesion. Mutation of the gene is associated with both cleft lip/palate-ectodermal dysplasia syndrome and orofacial cleft 7.
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