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Human TNFSF12 wild-type allele is located in the vicinity of 17p13 and is approximately 13 kb in length. This allele, which encodes tumor necrosis factor ligand superfamily member 12 protein, is involved in the promotion of angiogenesis. A readthrough that fuses this gene and the neighboring TNFSF13 gene may be expressed in activated T-cells and T- or B-cell lymphoma.
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