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  • Human HAVCR1 wild-type allele is located in the vicinity of 5q33.2 and is approximately 30 kb in length. This allele, which encodes hepatitis A virus cellular receptor 1 protein, plays a role in asthma, allergic reactions, hepatitis A binding and T-helper cell development. Polymorphism of the gene can modulate susceptibility to both hepatitis A infection and atopy.
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