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From the Sigmodon genus of rodents, Sigmodon hispidus was the first animal model to be used in polio research. It has a stout body, small ears and a dark coat that can be dark brown or mixed buff and black, with a tail length that is 35% of its total body length. As its name suggests, this breed has a proclivity for cotton in its nesting, and is a natural Hanta viral reservoir.
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