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Plethysmographs designed for non-invasive measuring and recording of data and graphics (i.e., a plethysmogram) of the volume and variations in the volume of the blood flow in the eyes due to the flow of blood in the ophthalmic artery (the first major branch of the internal carotid artery). Data is based on the measurement of the eye volume pressure waveform and amplitude. This technique is also known as ocular segmental plethysmography, and ocular pneumo plethysmography. These devices typically consist of a unit that measures, records, and displays the results, usually in graphic format, of the changes in the volume of the eye produced by pulsatile blood flow in the ophthalmic artery. The device also includes air-filled cups resembling contact lenses that apply vacuum to the sclera which results in occlusion of the ophthalmic artery and detect pulsatile changes in the eye pressure. The pressure at which systolic ocular pulsations reappear and its delay in time following occlusion is an indirect measurement of the ophthalmic artery pressure and consequently of the carotid artery pressure. A reduction in arterial pulse pressure in the eye and/or a delay in pulsation is a sign that a carotid artery may be blocked or narrowed.
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