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  • Ophthalmic solutions (typically riboflavin) designed for placing on the surface of the cornea to obtain a corneal collagen cross-linking when activated with ultraviolet A (UVA) light. The effect of the UVA on the solution placed on the cornea after activation is the formation of cellular bonds on the stromal layer with a corresponding strengthening of the cornea. These collagen cross-linking solutions are used in ophthalmic therapeutic procedures, such as keratoconus and ectasia (i.e., thinning) of the cornea following laser in-situ keratomileusis (LASIK) procedures ing laser in-situ keratomileusis (LASIK) procedures.
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