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Molecular assay reagents intended to identify mutations in the B-Raf proto-oncogene, serine/threonine kinase (BRAF) gene, located at chromosome 7q34, which encodes the serine/threonine-protein kinase B-Raf. Genetic variants at this locus have been associated with cardiofaciocutaneous syndrome 1, leopard syndrome 3, lung cancer, melanoma, and Noonan syndrome 7.
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