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  • Molecular assay reagents intended to identify mutations in the cytochrome P450 family 3 subfamily A member 5 (CYP3A5) gene, located at chromosome 7q21.1, which encodes the protein cytochrome P450 3A5. Genetic variants at this locus have been associated with essential hypertension. Additionally, the protein encoded by this gene is involved in drug metabolism and genetic variants at this locus have been associated with altered response to tacrolimus.
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