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  • Absence of ossification (assessed by absence of alizarin red stain) at a site which, in controls of the same age, is usually at least partially ossified. Applies only to the ossification site and does not imply any change to the bone precursor. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.)
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