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  • Pro-proteína convertase essencial para a homeostase do COLESTEROL. Liga-se ao RECEPTOR LDL (LDLR), ao receptor VLDL e ao receptor da apolipoproteína E (ver PROTEÍNA-1 RELACIONADA A RECEPTOR DE LIPOPROTEÍNA DE BAIXA DENSIDADE), sendo necessário para a sua degradação lisossômica. Também regula a APOPTOSE neuronal.
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