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Radiotherapy systems designed to administer ionizing radiation during a surgical procedure by means of electron beams of varying energies and/or high-energy photons using a mobile linear accelerator (linac) as a generator. These systems include a dedicated lightweight mobile linear accelerator that is mounted on a motorized gantry attached to a stand mounted on the transportation unit. The system can be transported from one to another conventional unshielded or reduce-shielding operating rooms; to prevent radiation exposure in adjacent rooms the systems may limit the beam energy to values limited to 10-12 mega-electron-volt, making they only able for targets to a few centimeter depth. Mobile intraoperative linear accelerators main components are similar to standard linear accelerators (i.e., a modulator, an electron gun, a radio-frequency power source, and an accelerator guide); the electron beam is further collimated to the desired size by on of a set of applicators (e.g., diameters from 3 to 10 cm) inserted into the patient. Some systems include adjustable gantries that can tilt and move in the horizontal plane. Mobile intraoperative radiotherapy systems are intended to provide a high dose of radiation in a single procedure with high target accuracy and low risk of damage to the adjacent tissues.
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