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Molecular assay reagents intended to identify gene variants associated with susceptibility to malignant hyperthermia, a severe reaction to certain pharmaceuticals that leads to a rapid rise in body temperature and uncontrolled muscle contractions. Genetic variants at multiple loci have been associated with susceptibility to malignant hyperthermia. These reagents are intended to detect various types of genetic changes (e.g., deletions, duplications, insertions, single nucleotide polymorphisms) in multiple malignant hyperthermia-susceptibility loci simultaneously.
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