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Molecular assay reagents intended to identify mutations in the Raf-1 proto-oncogene, serine/threonine kinase (RAF1) gene, located at chromosome 3p25.2, which encodes the protein RAF proto-oncogene serine/threonine-protein kinase. Genetic variants at this locus have been associated with dilated cardiomyopathy, LEOPARD syndrome, and Noonan syndrome.
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