PropertyValue
?:definition
  • A radioconjugate containing an androgen receptor (AR) targeting agent, 5-radioiodo-3\'-O-(17beta-succinyl-5alpha-androstan-3-one)-2\'-deoxyuridin-5\'-yl phosphate (RISAD-P), labeled with the radioisotope iodine I 125 ([125]I-RISAD-P), with potential use as an imaging agent for single photon emission computed tomography (SPECT) imaging. Upon administration, iodine I 125 RISAD-P selectively binds to and is taken up by AR. Upon SPECT imaging, AR-expressing tumor cells can be imaged and AR expression levels can be assessed. AR, which is overexpressed on certain tumor cells, plays key roles in tumor cell growth and survival.
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C4287592_NCI>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C4287592_NCI>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all