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  • A nuclear receptor family that binds oxysterols or bile acids and, after forming a heterodimer with a member of the retinoid X receptor (RXR) family, modulates the expression of genes that are involved in cholesterol, fatty acid, and glucose homeostasis. The members of this family include oxysterols receptor LXR-alpha (NR1H3), oxysterols receptor LXR-beta (NR1H2) and bile acid receptor (NR1H4).
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