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  • Level 1 Major Internal Structural Defect is defined by three criteria: first, the defects are prenatal in origin; second, the defect(s) affect (or have the propensity to affect) the health, survival, or physical or cognitive functioning of the individual; third, one of the following requirements must be met: a) For a live birth, alterations in the internal anatomy must be present at the time of live birth, must persist beyond the immediate peripartum period unless surgically repaired, and require confirmation of the diagnosis by definitive imaging study or intraoperative diagnosis; OR b) For a stillbirth, or for a spontaneous or therapeutic abortion, alterations in the internal anatomy must be detected during an autopsy, which are subsequently confirmed by documentation by a pathologist or other relevant subspecialist.
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