?:definition
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A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.
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