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Multimodal assay reagents intended to assess DNA quality; detect gene anomalies (i.e., mutations) in specific genes by DNA sequence analysis; and detect loss of heterozygosity at specific genetic loci. These multimodal assays incorporate the results of these tests along with separately generated cytology results into a predetermined algorithm that produces a score intended to aid in clinicians in determining disease diagnosis, prognosis, and/or treatment options.
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