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Multimodal assay reagents intended to detect gene anomalies (i.e., mutations) in specific genes by DNA sequence analysis and determine the presence, levels, and/or sub-cellular localization of specific analytes (e.g., carbohydrates, lipids, proteins) by immunocytochemistry/immunohistochemistry. These multimodal assays incorporate the results of these tests into a predetermined algorithm that produces a score intended to aid clinicians in determining disease diagnosis, prognosis, and/or treatment options.
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