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  • Vascular closure devices that utilize an extravascular clip to actively (i.e., mechanically) close the arteriotomy or venous puncture. They are designed to be percutaneously applied to an arterial puncture (arteriotomy) and/or venous puncture site, e.g., using a guide wire and delivery device. Typically, these devices are designed for use in the femoral artery and utilize an implantable clip made of nitinol.
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