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  • Human FGA wild-type allele is located in the vicinity of 4q31.3 and is approximately 8 kb in length. This allele, which encodes fibrinogen alpha chain protein, plays a role in blood clotting. Mutation of the gene is associated with congenital afibrinogenemia, familial visceral amyloidosis, congenital dysfibrinogenemia and congenital hypodysfibrinogenemia.
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