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  • An antitumor agent that inhibits thymidylate synthase, an enzyme that catalyses the de novo synthesis of deoxythymidylate and acts as a key rate-limiting enzyme of DNA synthesis. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2021\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2021\' NCI Thesaurus)
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