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  • Compounds causing hyperacetylation of histone deacetylase, an enzyme involved in the regulation of transcription, causing inhibition of cell differentiation and induction of apoptosis. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1946\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1946\' NCI Thesaurus)
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