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Administration device intended to house a cartridge that contains a sterile, single-dose or multidose, parenteral preparation. It is usually supplied without a fixed needle, and may or may not be fitted with a needle safety device. The cartridge is usually replaceable when it is empty. The pre-defined dose, which may or may not be adjustable, is administered via an actuation, such as the pressing of a button. Dose dispenser is excluded. Comment: When a pen is supplied with an integral cartridge that cannot be replaced and the pen is intended to be disposed of once it is empty, it is considered to be a pre-filled pen.
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