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Molecular assay reagents intended to identify acquired genetic variants (i.e., somatic mutations) associated with gastrointestinal stromal tumors (GISTs), malignant growths arising from autonomic nervous system cells (i.e., interstitial cells of Cajal) in the walls of the digestive system. Somatic mutations in multiple loci have been observed in GISTs. These reagents are intended to detect somatic mutations in multiple GIST-associated loci simultaneously.
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