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  • Implantable radiopaque and/or ultrasonographically detectable markers used during breast biopsy procedures to mark the site of the biopsied breast lesion. Breast biopsy markers typically consist of a small, radiopaque metallic (e.g., nitinol, stainless steel, titanium) or non-metallic (e.g., carbon-coated ceramic) implant in one of several distinctive shapes (e.g., barbell, coil, ribbon, ring, wing). Some markers are complexed with or embedded in collagen, polymer, or hydrogel, which may improve ultrasonographic detection and/or decrease the risk of marker migration. Breast biopsy markers are typically supplied preloaded in an applicator, which may consist of a needle for direct percutaneous access to the lesion or an applicator designed to access the lesion via a biopsy system probe. Biopsy site markers facilitate the localization of biopsied lesions that may no longer be detectable by imaging following the biopsy and/or subsequent treatment (e.g., neoadjuvant chemotherapy).
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