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  • A preparation of autologous cytotoxic T lymphocytes (CTLs) genetically modified to target a not yet disclosed ovarian cancer-specific tumor-associated antigen (TAA), with potential immunomodulating and antineoplastic activities. After isolation, transduction, expansion in culture, and reintroduction into the patient, the autologous ovarian cancer-specific cytotoxic T lymphocytes (OC-CTLs) bind to and induce selective toxicity in tumor cells expressing the TAA.
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