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  • Human FEM1C wild-type allele is located in the vicinity of 5q22.3 and is approximately 24 kb in length. This allele, which encodes protein fem-1 homolog C, plays a role in ubiquitin protein-ligase activity. A fusion involving this gene and the SEMA6A gene may be associated with B-cell acute lymphoblastic leukemia (B-ALL).
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