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A donor-derived microbiome therapeutic composed of a combination of as of yet not disclosed microbes that were specifically selected to incorporate the bacterial signature found in melanoma patients who have a robust response to immunotherapy, with potential immunomodulating activity. Upon administration, SER-401 may restore the unhealthy, altered gut microbiome, enhance the microbial diversity and function in the gastrointestinal (GI) tact and may re-establish a healthy microbiome in the GI tract. This may enhance the patients\' immunological activity and improve patients\' response to immunotherapy.
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