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  • A vaccine consisting of dendritic cells (DCs) that are modified with lentivirus vectors expressing engineered SARS-CoV-2 minigenes SMENP and immune modulatory genes, with potential immunizing activity against SARS-CoV-2. Upon administration, SARS-CoV-2 lentiviral-based DC vaccine LV-SMENP-DC may elicit a specific cytotoxic T-cell (CTL) response against the SARS-CoV-2 viral antigens encoded by the minigenes.
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