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  • A vaccine consisting of DNA plasmid encoding the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) surface antigen spike (S) protein, with potential immunizing activity against SARS-CoV-2. Upon administration of the SARS-CoV-2 S-protein DNA vaccine GX-19 via intramuscular injection followed by electroporation (EP), the DNA plasmids enter the cells and the cells produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection. S-protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.
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