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  • Systems designed to achieve a uniformity of solutes (ions, small molecules, biomolecules, etc.), solvents, and/or suspended particles such as colloids in various microliter volumes. Microfluidic mixing systems have a mixing chip or cassette containing microchannels used for the processing of liquids. As part of the system, a pump or syringe mechanism moves the liquid to inside the mixing cassette. Mixing cassettes have two or more inlet ports and an outlet port. Most microfluidic mixing systems have adjustable input parameters, including flow rate ratios, component flow rate, and total flow rate. Passive mixing systems have microchannel configurations specifically designed to increase either the contact area or the contact time (or both). Active mixing systems apply an external force to the sample flows to accelerate the diffusion process. Microfluidic mixing systems can be used to form nanomedicines by encapsulating substances (genetic material, vaccines, contract media, etc.) in lipids, polymers, or liposomes by precisely mixing liquids that contain the different components.
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