PropertyValue
?:definition
  • A radioconjugate composed of FAP-2286, a fibroblast activation protein (FAP)-targeted peptide, attached to a linker and tetraazacyclododecane tetraacetic acid chelator, conjugated to the radioisotope gallium Ga 68, with potential use as a tracer for FAP-expressing cancer-associated fibroblasts (CAFs) during positron emission tomography (PET). Upon administration of gallium Ga 68 FAP-2286, the FAP-2286 moiety targets and binds to FAP-expressing CAFs. Upon binding, FAP-expressing cells can be detected during PET imaging. FAP, a cell surface protein, is overexpressed on CAFs in the tumor microenvironment (TME).
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C5447255_NCI>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C5447255_NCI>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all