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A dietary supplement containing chocolate derived from the cacao bean, with potential vasodilating, anti-inflammatory, antioxidant, cardiovascular protective and neuroprotective activities. Chocolate contains flavonoids, including epicatechin, catechin, procyanidins and xanthines, such as theobromine, and trace minerals. Upon oral administration, the bioactive ingredients in the chocolate-based dietary supplement may inhibit angiotensin-converting enzyme (ACE) and increase the production of nitric oxide (NO) through the activation of endothelial nitric oxide synthase (eNOS). This may result in vasodilation, improve blood flow, and decrease blood pressure. The chocolate-based dietary supplement also may improve insulin sensitivity, enhance cognition, and decrease the production of pro-inflammatory molecules. In addition, chocolate-based dietary may exert antioxidant effects and scavenge reactive oxygen species (ROS), thereby protecting cells from oxidative stress and DNA damage.
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