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Much has changed in the medical treatment of COVID-19 after the first patient with an infection with SARS-CoV-2 in the Netherlands was diagnosed in February 2020 On the basis of limited data, at first only off-label use of (hydroxy)chloroquine seemed to be a treatment option However, now based on the findings of several randomized studies, other medicines have been included in the Dutch guidelines about the treatment of COVID-19 In this article, we will briefly discuss the current state of affairs with regard to the drugs (hydroxy) chloroquine, remdesivir and corticosteroids Again, it appears that only well-executed randomized clinical trials can determine the status of various supposedly effective drugs
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