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COVID- 19 has become a major pandemic affecting more than 11 million people worldwide Common radiological manifestations of COVID-19 include peripheral based ground-glass or consolidative opacities;however, pneumothorax and pneumo-mediastinum are very rare manifestations;even more so within patients not on mechanical ventilation We present a case series of 5 patients with COVID-19 who either presented with or developed spontaneous pneumothorax or pneumo-mediastinum within the course of hospitalization With the exception of one patient, all other patients developed pneumothorax as a late manifestation in their illness;more than 10 days after initial symptom onset in COVID-19 From within this case series, all patients who developed spontaneous pneumothorax or pneumo-mediastinum during hospitalization subsequently succumbed to the illness Spontaneous pneumothorax or pneumo-mediastinum may be an important late manifestation in COVID-19;even in spontaneously breathing patients This may be related to development of cystic changes within the lung parenchyma Although the clinical relevance of this finding is unknown;in our series, it portended a worse prognosis in the majority of patients
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The_American_Journal_of_the_Medical_Sciences
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Pneumothorax and Pneumomediastinum in COVID-19: A Case Series
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