PropertyValue
?:abstract
  • A review COVID-19 was outbroken in all over the world The current clin treatment is dependent on old drugs However, the pharmacokinetic parameters of all these drugs in COVID-19 are very limited, furthermore, there are some therapeutic factors (such as hemodialysis, and Extracorporeal Membrane Oxygenation (ECMO)) affecting pharmacokinetic parameters So it is very necessary to perform therapeutic drug monitoring, in order to improve clin efficacy and decrease drug adverse reactions In this work, we reviewed the TDM development of hydroxychloroquine, teicoplanin, arbidol, lopinavir (LPV)/Ritonavir (RTV), and vancomycin used in COVID-19 patients, including the TDM progress of these drugs in other diseases, concentration detection methods (mainly liquid chromatograph tandem mass spectrometry), therapeutic window range, and the TDM development of these drugs in COVID-19 patients This review can provide methodol support for TDM research, and provide theor basis for individualized medication of COVID-19
is ?:annotates of
?:creator
?:journal
  • Open_Access_(OA)_Online-First_Publ._Res._Pap._COVID-19
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Progress in therapeutic drug monitoring of 2019 novel coronavirus pneumonia
?:type
?:who_covidence_id
  • #2059
  • #661137
?:year
  • 2020

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