?:abstract
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The SARS-CoV-2 virus causes a respiratory distress syndrome, the main symptom of COVID-19 (for \'COronaVIrus Disease 2019\') This infectious disease has been causing a major health and socio-economic pandemic since December 2019 The pulmonary alveolus is regarded as the main target of SARS-CoV-2 However, this coronavirus is capable of directly or indirectly affecting other organs, including the kidneys Here, we summarize the presumed pathophysiology of COVID-19 renal disease The incidence of acute kidney injury ranges from 0,5 to 22 % of all patients infected with SARS-CoV-2 The need for renal replacement therapy is reported in 5-9 % of patients in intensive care Histological analysis of renal biopsies mainly shows acute tubular necrosis of varying severity, as well as the congestion of glomerular and peri-tubular capillaries Endothelitis has been described in few cases Evidence for a factual inflammation of the glomerulus remains controversial The medium/long term consequences of COVID-19 nephropathy are unknown and will deserve a tight follow-up
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