bvm5783t

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?:abstract	BACKGROUND AND GOALS: The aim of the study is to know the prevalence of SARS-CoV-2 infection in patients and professional staff of a medium or long-stay hospital during the peak period of the pandemic in Spain, spring 2020 MATERIAL AND METHODS: At the end of February 2020, we developed at the hospital a strategy to diagnose the SARS-CoV-2 infection consisting of complementing the realization of PCR tests at real time with a quick technique of lateral flow immunochromatography to detect IgG and IgM antibodies against the virus We also developed a protocol to realize those diagnostic tests and considered an infection (current or past) a positive result in any of the above tests We included 524 participants in the study (230 patients and 294 hospital staff), and divided them into hospital patients and Hemodialysis outpatients Furthermore, we divided the hospital staff into healthcare and non-healthcare staff The documented period was from March, 20th to April, 21st, 2020 RESULTS: 26 out of 230 patients tested positive in any of the diagnostic techniques (PCR, antibodies IgG, IgM) with a 11 30% prevalence According to patients groups, we got a 14 38% prevalence in hospital patients vs 5 95% in outpatients, with a significantly higher risk in admitted patients after adjustment for age and gender (OR=3,309, 95%CI: 1,154-9,495) 24 out of 294 hospital staff tested positive in any of the diagnostic techniques, with a 8 16% prevalence According to the groups, we got a 8 91% prevalence in healthcare staff vs 4 26% in non-healthcare staff Thus, we do not see any statistically significant differences between hospital staff and patients as far as prevalence is concerned (P=0,391), (OR=2,200, 95%CI: 0,500-9,689) CONCLUSIONS: The result of the study was a quite low prevalence rate of SARS-CoV-2 infection, in both patients and hospital staff, being the hospital patients\' prevalence rate higher than the outpatients\', and the healthcare staff higher than the non-healthcare\'s Combining PCR tests (gold standard) with antibodies tests proved useful as a diagnostic strategy
is ?:annotates of	<https://research.tib.eu/covid-19/entity/bvm5783t_hasAnnotation_C0042776> <https://research.tib.eu/covid-19/entity/bvm5783t_hasAnnotation_C1175743> <https://research.tib.eu/covid-19/entity/bvm5783t_hasAnnotation_C1824370> <https://research.tib.eu/covid-19/entity/bvm5783t_hasAnnotation_C4284302>
?:creator	<https://research.tib.eu/covid-19/entity/Moreno_Borraz%2C_L._A.%3B_Gimenez_Lopez%2C_M.%3B_Carrera_Lasfuentes%2C_P.%3B_Gonzalez_Perez%2C_E.%3B_Ortiz_Domingo%2C_C.%3B_Bonafonte_Marteles%2C_J._L.%3B_Vicente_Gaspar%2C_C.%3B_Amoros_de_la_Nieta%2C_F.%3B_Sastre_Heres%2C_A.%3B_Garcia_Forcada%2C_A._L.%3B_Serrano_Herrero%2C_M._P.%3B_Fernandez_Doblado%2C_S.%3B_Espinosa_Val%2C_M._C.%3B_Fernandez_Adarve%2C_M._M.%3B_Narvion_Carriquiri%2C_A.%3B_Arto_Maza%2C_F.%3B_Barea_Gil%2C_M.%3B_Aznar_Vazquez%2C_I.%3B_Sisas_Rubio%2C_R.%3B_Gonzalez_Tejedor%2C_R.%3B_Florentin_Ostariz%2C_E.%3B_Lopez_Santed%2C_C.%3B_Molina_Morales%2C_A._R.%3B_Parrilla_Binue%2C_S.%3B_Perez_Sans%2C_J.%3B_Garcia_Mena%2C_M.%3B_Moragrega_Cardona%2C_B.%3B_Luzon_Alonso%2C_M.%3B_Diaz_Mora%2C_F.%3B_Gil_Acebes%2C_J._C.%3B_Rubio_Morilla%2C_Y.%3B_Lou_Lou%2C_R.%3B_Zabala_Lahoz%2C_R._B.%3B_Coarasa_Liron_de_Robles%2C_A.>
?:journal	Revista_Espanola_de_Geriatria_y_Gerontologia
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:source	WHO
?:title	[Prevalence of SARS-CoV-2 coronavirus infection in patients and professional staff at a medium or long-stay hospital in Spain]
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#974550
?:year	2020

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Value

?:abstract

BACKGROUND AND GOALS: The aim of the study is to know the prevalence of SARS-CoV-2 infection in patients and professional staff of a medium or long-stay hospital during the peak period of the pandemic in Spain, spring 2020 MATERIAL AND METHODS: At the end of February 2020, we developed at the hospital a strategy to diagnose the SARS-CoV-2 infection consisting of complementing the realization of PCR tests at real time with a quick technique of lateral flow immunochromatography to detect IgG and IgM antibodies against the virus We also developed a protocol to realize those diagnostic tests and considered an infection (current or past) a positive result in any of the above tests We included 524 participants in the study (230 patients and 294 hospital staff), and divided them into hospital patients and Hemodialysis outpatients Furthermore, we divided the hospital staff into healthcare and non-healthcare staff The documented period was from March, 20th to April, 21st, 2020 RESULTS: 26 out of 230 patients tested positive in any of the diagnostic techniques (PCR, antibodies IgG, IgM) with a 11 30% prevalence According to patients groups, we got a 14 38% prevalence in hospital patients vs 5 95% in outpatients, with a significantly higher risk in admitted patients after adjustment for age and gender (OR=3,309, 95%CI: 1,154-9,495) 24 out of 294 hospital staff tested positive in any of the diagnostic techniques, with a 8 16% prevalence According to the groups, we got a 8 91% prevalence in healthcare staff vs 4 26% in non-healthcare staff Thus, we do not see any statistically significant differences between hospital staff and patients as far as prevalence is concerned (P=0,391), (OR=2,200, 95%CI: 0,500-9,689) CONCLUSIONS: The result of the study was a quite low prevalence rate of SARS-CoV-2 infection, in both patients and hospital staff, being the hospital patients\' prevalence rate higher than the outpatients\', and the healthcare staff higher than the non-healthcare\'s Combining PCR tests (gold standard) with antibodies tests proved useful as a diagnostic strategy

is ?:annotates of