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[Image: see text] Intensified efforts to curb transmission of the Severe Acute Respiratory Syndrome Coronavirus-2 might lead to an elevated concentration of disinfectants in domestic wastewater and drinking water in China, possibly resulting in the generation of numerous toxic disinfection byproducts (DBPs). In this study, the occurrence and distribution of five categories of DBPs, including six trihalomethanes (THMs), nine haloacetic acids (HAAs), two haloketones, nine nitrosamines, and nine aromatic halogenated DBPs, in domestic wastewater effluent, tap water, and surface water were investigated. The results showed that the total concentration level of measured DBPs in wastewater effluents (78.3 μg/L) was higher than that in tap water (56.0 μg/L, p = 0.05), followed by surface water (8.0 μg/L, p < 0.01). Moreover, HAAs and THMs were the two most dominant categories of DBPs in wastewater effluents, tap water, and surface water, accounting for >90%, respectively. Out of the regulated DBPs, none of the wastewater effluents and tap water samples exceeded the corresponding maximum guideline values of chloroform (300 μg/L), THM4 (80 μg/L), NDMA (100 ng/L), and only 2 of 35 tap water samples (67.6 and 63.3 μg/L) exceeded the HAA5 (60 μg/L) safe limit. HAAs in wastewater effluents showed higher values of risk quotient for green algae. This study illustrates that the elevated use of disinfectants within the guidance ranges during water disinfection did not result in a significant increase in the concentration of DBPs.
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