PropertyValue
?:abstract
  • Aim: Whole genome and peptide mutation analysis can specify effective vaccine and therapeutics against severe acute respiratory coronavirus-2 (SARS-CoV-2) Materials & methods: Whole genome similarity for Bangladeshi SARS-CoV-2 was determined using ClustalW and BLASTn Phylogenetic analysis was conducted using neighbor-joining method Results: 100% of isolates in Bangladesh were in the G clade We found 99 98-100% sequence similarity among Bangladeshi isolates and isolates of England, Greece, USA, Saudi Arabia and India Deletion of bases at 5 \' untranslated region and 3 \' untranslated region was detected Substitution 261 (E -> D) at NSP13 and 1109 (F -> L) at spike (S) protein were detected Substitution 377 (D -> G) at nucleocapsid with common substitution 614 (D -> G) at S were also detected Conclusion: This study will provide baseline data for development of an effective vaccine or therapeutics against SARS-CoV-2
is ?:annotates of
?:creator
?:journal
  • Future_Virology
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Phylogenetic and whole genome analysis of first seven SARS-CoV-2 isolates in Bangladesh
?:type
?:who_covidence_id
  • #969284
?:year
  • 2020

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