PropertyValue
?:abstract
  • In 2019, a new human pandemic coronavirus (SARS-CoV-2) emerged in Wuhan, China We present the knowledge about SARS-CoV-2 compared to SARS-CoV and MERS-CoV The SARS-CoV-2 is similar to other coronaviruses, nevertheless, differenceswere observed Cell entry of SARS-CoV-2 is facilitated by cleavage of spike protein by furin The receptor-binding motif of SARS-CoV-2 spike protein forms a larger binding interface and more contacts with host receptor ACE2 compared those of in SARS-CoV Unlikeother coronaviruses, the SARS-CoV-2 spike protein has a motif, known to bind integrins Nucleocapsid protein and RNA-dependent RNA polymerase of SARS-CoV-2 display some structural differences compared to those of SARS-CoV as well These features may increase the efficiency of the spread of SARS-CoV-2 and indicate the putative targets for specific antiviral therapy
is ?:annotates of
?:creator
?:journal
  • Postepy_Mikrobiologii
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Sars-cov-2 and betacoronavirus: What have we learned in 8 months?
?:type
?:who_covidence_id
  • #884145
?:year
  • 2020

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