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?:abstract
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UNSTRUCTURED One Digital Health (ODH) is proposed as a unified structure. The One Digital Health \'Steering Wheel\' conceptual framework is built around two keys (One Health and Digital Health), three perspectives (Individual Health and well-being, Population and Society, and Ecosystem), and five dimensions (Citizen\'s engagement, Education, Environment, Human and Veterinary Healthcare, and Healthcare Industry (4.0). The focus is on the digital transformation of future health ecosystems, bridging a systemic approach of health and life sciences with a broad digital technology perspective to cover human and animal health, with the management of the surrounding environment. This allows to examine how next generations of health informaticians can address the intrinsic complexity of novel health and care scenarios in the digitally transformed health ecosystems. In the emerging hybrid landscape, citizens and their health data are called to play a central role viewed through an individual and population lens. ODH\'s main challenge consists in facilitating and improving interaction between communities of \'One Health\' and \'Digital Health\' for efficient interactions to deliver near-real time data-driven contributions to systems medicine and systems ecology. Therefore, digital health literacy, capacity to build understanding and engage in health prevention activities, self-management and collaboration, to prevent, control and alleviate potential problems, are necessary for systemic ecosystem-driven public health and data science research. To this purpose a healthy One Digital Health ecosystem must become an active and forceful approach for preventing and managing health crises and disasters such as the COVID-19 pandemic.
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