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?:abstract
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A primigravid woman with Covid-19 related respiratory insufficiency was admitted into a tertiary Intensive Care Unit at 23 3/7 weeks’ gestation. Highly sensitive flow cytometry of peripheral leukocytes indicated significantly suppressed naïve T- and B-cell compartments. The suppressed immune cell responses led us keep the initially started administration of corticosteroids for fetal and maternal indication at a low dose. After three weeks her B-cell response peaked, SARS-CoV-2 was cleared and clinical improvement ensued a week later. At 28 weeks’ gestation, a son of 1570 g was born by cesarean section. She was extubated two days postpartum and discharged from hospital 5.5 weeks postpartum.
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?:doi
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10.1016/j.jri.2020.103243
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document_parses/pdf_json/57fe154d6b1531d4cb810b1880d6343ff32c405c.json
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document_parses/pmc_json/PMC7598537.xml.json
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?:title
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Detailed immune monitoring of a pregnant woman with critical Covid-19
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